Strongest Anti Estrogen Letrozole Femara Medication For Infertility CAS 112809-51-5
Letrozole is used for:
Primarily treating certain kinds of breast cancer in women past menopause. It may also be used for other conditions as determined by your doctor.
Letrozole is an aromatase inhibitor. It works by reducing the total amount of estrogen produced primarily in the body. This helps to starve cancer cells by depriving them of estrogen.
Do NOT use letrozole if:
you are allergic to any ingredient in letrozole
you have not started menopause
Contact your doctor or health care provider right away if any of these apply to you.
Letrozole is an anti-estrogen of the Aromatase Inhibitor (AI) family and is one of the most potent and powerfully effective of all AI’s. In fact, its potency is sometimes too much for some to handle when used for off label use. Letrozole first gained U.S. FDA approval in 1997 and would hit the market under the brand name Femara through Novartis. Although Femara is the dominating trade name of the AI, unlike most AI’s it is the only one generally known by its chemical name Letrozole far more commonly than its dominating brand name.
Letrozole was first developed in an effort to combat breast cancer in post-menopausal women. In fact, it would prove to be virtually identical to the already popular AI in Arimidex (Anastrozole). While intended for breast cancer treatment, like many AI’s, it has found a welcomed home among anabolic steroid users. Letrozole is one of the most commonly used anti-estrogens among steroid users during steroid use to combat possible estrogenic related side effects. It is so effective as an anti-estrogen in this regard many anabolic steroids have effectively reversed gynecomastia symptoms with Letrozole.
Letrozole dosages and cycles:
In the treatment of breast cancer, the standard Letrozole dose will normally be 2.5mg per day. This is an extremely potent dose and will normally be administered until the cancer subsides. In many cases, at the point of remission the patient will switch from Letrozole to Nolvadex in a preventative treatment plan scenario.
For the anabolic steroid user, Letrozole doses will normally be much lower. Even with the use of anabolic steroids, a 2.5mg dosing will normally be too high and could potentially drain the individual of energy; in fact, it’s almost guaranteed. The only exception we could make for such a dose would be to combat early gynecomastia symptoms. If symptoms begin to show 7-14 days at a dose of 2.5mg per day can reverse the symptoms. Once symptoms begin to fade away the individual should be able to tapper down to a more manageable dose and maintain it for the remainder of the cycle. If this doesn’t work there’s a good chance the symptoms have already set in beyond remedy. When this happens the only thing that will remove your gynecomastia is surgery. For standard estrogenic related protection, most men will find 0.5-1mg every other day to be more than enough. When used as an anti-estrogen in low testosterone treatment plans, even less may be needed. For the competitive bodybuilder, the final 7-14 days before competition, a full 1mg per day leading up to the show can be a solid dose and will greatly help with dryness and a tighter look. This is, however, not a dose most would want to maintain for an extended period of time as it can be harsh.
There are several AI’s available on the market. Arimidex is probably the most common AI with Aromasin (Exemestane) gaining a lot of popularity in recent years. However, there are many who find Letrozole to be the most effective. In the end, many will simply need to try all three at different times to find which one works best for them. You will never need all three and even if you end up preferring Arimidex or Aromasin you will find Letrozole should still work for most anyone.
Before using letrozole:
Some medical conditions may interact with letrozole. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
if you are pregnant, planning to become pregnant or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines or other substances
if you have liver problems or high cholesterol
if you are still having menstrual periods or have not completely finished menopause
if you are taking hormone replacement therapy (HRT)