Pharmaceutical Estrogenic Steroids Estradiol Benzoate For Female Sex Hormone Enhancement

Quick details of Estradiol Benzoate
Product name: Estradiol Benzoate
Synonyms: 17beta)-Estra-1,3,5(10)-triene-3,17-diol 3-benzoate;1,3,5(10)-Estratriene-3,17-diol-3-benzoate;1,3,5(10)-Oestratriene-3,17-beta-diol 3-benzoate;1,3,5(10)-oestratriene-3,17-beta-diol3-benzoate;17beta-Estradiol monobenzoate;17-beta-estradiolmonobenzoate;17-beta-Oestradiol 3-benzoate;17-beta-oestradiol3-benzoate
CAS Registry Number: 50-50-0
Molecular Formula: C25H28O3
Molecular weight: 376.49
EINECS Number: 200-043-7
Assay:99.51%
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COA of  Estradiol Benzoate Powder

TEST ITEMS

SPECIFICATION

RESULTS

Description

White crystalline powder

White crystalline powder

Assay

99.0~103.0%

99.51%

Melting Point

192~198°C

192~196°C

Loss On Drying

0.5%max

0.21%

Related Substances

total impurities ≤1.0%

conform

Related Substances

any individual impurity ≤0.5%

conform

Conclusion

The specification conform with enterprise standard

Estradiol benzoate-powder

What is estradiol benzoate?
Estradiol benzoate is a derivative of estradiol, can promote endometrial hyperplasia, enhance uterine smooth muscle contraction, promote breast ductal dysplasia, promote and regulate the normal development of female sexual organs and sexual characteristics. But a larger dose can inhibit the release of prolactin in the anterior pituitary, thereby reducing milk secretion. The goods have anti-androgen effects, and lower blood cholesterol, increased calcium in the bone calm.

What are the properties of estradiol benzoate?
The product is white crystalline powder; odorless. The product is slightly soluble in acetone, in ethanol or plants
Estradiol benzoate
Estradiol benzoate
The oil is slightly soluble and insoluble in water. Melting point: the melting point of the goods (Appendix Ⅵ C) is 191 ~ 196 ℃. Specific rotation: take the goods, accurately weighed, plus dioxane dissolved and quantitative dilution made per 1ml containing 10mg of the solution, according to the determination (Appendix Ⅵ E), the specific rotation of +58 ° to + 63 ° The Absorption coefficient: take the goods, accurately weighed, add ethanol dissolved and diluted to produce 10μg per 1ml of the solution, according to spectrophotometry (Appendix Ⅳ A), measured at the wavelength of 230nm absorbance, absorption coefficient ( E1% 1cm) is 490 to 520.

Estradiol-benzoate-powder

what are the usages of estradiol benzoate?
1. Uterine hypoplasia, amenorrhea or menstruation less secondary or primary ovarian function is too low due to lack of estrogen secretion can affect the uterus, genitalia and secondary sexual characteristics of the normal development of estrogen and progesterone sequential application can be Produce similar physiological changes in adolescence.

How to store estradiol benzoate?
Store in a cool, dry place. Stored in a closed container.