Anti Estrogen Oral Anabolic Steroids Nolvadex Tamoxifen Citrate to Antitumor CAS 54965-24-1

Anti Estrogen Oral Anabolic Steroids Nolvadex Tamoxifen Citrate to Antitumor CAS 54965-24-1

Effects of Tamoxifen Citrate:
For the anabolic steroid user the positive effects of Tamoxifen Citrate can be seen both during and post anabolic steroid use with post use being primary. Anabolic steroids like Testosterone and Nandrolone among others will increase the body’s serum estrogen levels. This occurs by the testosterone hormone converting to testosterone, which happens due to it being metabolized by the aromatase enzyme. Once aromatized you have more estrogen, and this can lead to gynecomastia and water retention. It can also lead to high blood pressure if water retention becomes severe. Tamoxifen Citrate does not lower serum estrogen levels, but it will bind to the receptors in the chest preventing the estrogen from binding. It will not do a lot for water retention if that is an issue. It is also not enough gynecomastia protection for all men, but that depends on how high estrogen levels go as well as genetics. If more or stronger protection is needed Aromatase Inhibitors (AI’s) are recommended. AI’s are anti-estrogens that inhibit aromatase activity and lower serum estrogen levels.

nolvadex-tamoxifen-citrate

We then have the testosterone stimulating effects of Tamoxifen Citrate. This is by far the most important effect for the anabolic steroid user. When we use anabolic steroids we suppress our natural testosterone production, and this will occur regardless of the steroids used. Steroid use creates a negative feedback and tells your pituitary to stop making LH and FSH. This is why almost all steroid cycles include exogenous testosterone so that the negative feedback doesn’t cause a low testosterone level. Once steroid use is complete something is then needed to jump start testosterone production. It will occur on its own, but it will be slow and Tamoxifen can both speed it up and make it more efficient. Tamoxifen Citrate is introduced, LH and FSH levels go up and as a result testosterone is produced.

Important Note: PCT use that includes Tamoxifen Citrate or any SERM, for it to be successful this assumes no prior low testosterone condition existed. It also assumes no damage was done to the Hypothalamic-Pituitary-Testicular-Axis (HPTA) during use. If prior low levels existed Tamoxifen Citrate won’t magically fix this. If severe damage was done to the HPTA you will not recover and may be in need of low testosterone treatment.

Important Note: Many steroid users believe that a good PCT brings about full recovery, but this is a false belief. A PCT that includes Tamoxifen Citrate will stimulate recovery, but it will not end it. It will still take several months for full recovery to occur, but it stands a much better chance with PCT than without.

For the breast cancer patient the effects of Tamoxifen Citrate are perhaps even more straightforward than they are for the anabolic steroid user. Estrogen attaches and feeds the cancer, but Tamoxifen Citrate prevents it from attaching and starves the cancer. This is a simple yet effective means of treatment. This is not the only drug used in treatment; commonly treatment will begin with an AI and then will be switched to a SERM like Tamoxifen Citrate. It is also sometimes used as a preventative measure in those that have a strong family history of breast cancer.

Tamoxifen Citrate Dosages and cycles:
For the purpose of breast cancer treatment there are six Tamoxifen Citrate plans that encompass both male and female treatment. In any of the six plans doses normally fall in the 10-20mg twice per day range. A full 40mg per day (20mg twice per day) is very common during the first stage of Tamoxifen Citrate treatment. Many breast cancer patients will also continue 10-20mg per day indefinitely once the cancer is in remission in order to prevent it from coming back.

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We then have the anabolic steroid user. For on cycle gynecomastia prevention 10-20mg per day is the standard range. If this dosing range does not help it is unlikely any dose will and AI’s should strongly be considered. Some men are afraid to use AI’s because they fear they might hinder their gains. It’s true you will hold less water therefore weigh less, but water is not an actual gain. Besides, would you rather weigh just a little less or have massive and unattractive gynecomastia?

We’re then left with PCT use. Most PCT plans will begin with Tamoxifen Citrate doses of 40mg per day and will continue at this dose for 2-3 weeks. The dose will then be reduced to 20mg per day and will continue at this dose for 2-3 weeks. For a proper PCT it will often include another SERM Clomiphene Citrate (Clomid). For a full PCT outline please see How to Come off Steroids.

What is tamoxifen:
Tamoxifen blocks the actions of estrogen, a female hormone. Certain types of breast cancer require estrogen to grow.
Tamoxifen is used to treat some types of breast cancer in men and women. It is also used to lower a woman’s chance of developing breast cancer if she has a high risk (such as a family history of breast cancer).
Tamoxifen may also be used for purposes not listed in this medication guide.

Important information
Do not use tamoxifen if you are pregnant. It could harm the unborn baby. Use a barrier form of birth control (such as a condom or diaphragm with spermicide) while you are using this medication and for at least 2 months after your treatment ends. You should not use tamoxifen if you are allergic to it, or if you have a history of blood clots in your veins or your lungs, or if you are also taking a blood thinner such as warfarin (Coumadin).

Before taking this medicine
You should not use tamoxifen if you are allergic to it.
You should not use tamoxifen to reduce your risk of breast cancer if you are also taking a blood thinner such as warfarin (Coumadin, Jantoven).

Do not take tamoxifen if you are pregnant. It could harm the unborn baby. Avoid becoming pregnant while you are using this medicine, and for at least 2 months after your treatment ends.

Hormonal contraception (such as birth control pills, injections, implants, skin patches, and vaginal rings) may not be effective enough to prevent pregnancy while taking tamoxifen. Ask your doctor about using non hormonal birth control (condom, diaphragm with spermicide, or intrauterine device/IUD).

If you are taking tamoxifen to reduce your risk of breast cancer, you may need to take your first dose while you are having a menstrual period. You may also need to have a pregnancy test before you start taking tamoxifen, to make sure you are not pregnant. Follow your doctor’s instructions.

Taking tamoxifen may increase your risk of uterine cancer, stroke, or a blood clot in the lung, which can be fatal. Talk with your doctor about your specific risks in taking this medicine.