Anabolic Steroid Mesterolone Proviron for Muscle Building
Proviron Functions & Traits:
Mesterolone is a dihydrotestosterone (DHT) derived anabolic androgenic steroid. Specifically it is a structurally altered DHT hormone possessing the addition of a methyl group at the carbon one position. This allows the hormone to survive oral ingestion by protecting it from hepatic breakdown. This is one of the only oral anabolic steroids that is not C17-alpha alkylated (C17-aa) but instead carries the added methyl group. Oral Primobolan is the other most well-known oral steroid that carries this same methyl group. While the added methyl group does in fact protect it from breakdown, the total bioavailability of Proviron will be far less than most all C17-aa oral steroids. For this reason it has fallen out of popularity among many performance enhancing athletes but as we will see perhaps unjustifiably so.
Proviron carries an androgenic rating of 30-40 and an anabolic rating of 100-150. All ratings derive from and are measured against testosterone, which carries a rating of 100 in both categories. Despite having an anabolic rating that is potentially greater than testosterone, Proviron will display very low anabolic traits. This is very similar to Halotestin (Fluoxymesterone), which carries a massive anabolic rating but very little translatable anabolic activity. In the case of Proviron, while structurally very anabolic, the Mesterolone hormone converts and reduces to Diol metabolites, in turn reducing anabolic activity. However, Proviron’s androgenic rating is a different story. In fact, its translatable androgenic activity appears to commonly be higher than its structural rating would imply.
On a functional basis, Proviron carries four primary traits that largely define its mode of action. First and foremost the Mesterolone hormone has a strong binding affinity to Sex-Hormone-Binding-Globulin (SHBG). In fact, it appears to be one of the strongest anabolic steroids in this regard. By binding to SHBG, a hormone partially responsible for reducing free testosterone, binding SHBG will enhance the amount of circulating free testosterone. More importantly for the anabolic steroid user, it will make a larger percentage of the anabolic steroids used available in a free rather than bound state. A simple way to look at it is the anabolic steroids you’re taking become more powerful and potent.
Proviron also has the ability to interact with the aromatase enzyme, the enzyme responsible for the conversion of testosterone to estrogen. By binding to the aromatase enzyme, Proviron can actually inhibit aromatase activity, thereby offering protection against estrogenic side effects. It will not carry an anti-estrogenic effect near the level of power of an Aromatase Inhibitor (AI) but it will be notable. Depending on the nature of the cycle the individual undertakes it is quite possible for Proviron to take care of all your anti-estrogen needs.
The Mesterolone hormone will also carry a strong binding affinity to the androgen receptor. Once again this will promote the functionality of other steroids to a degree but more importantly promote enhanced metabolic activity through direct lipolysis. Then we’re left with the final issue that surrounds Proviron as a fertility medication. This is an anabolic steroid that does not suppress gonadotropins similarly to other anabolic steroids. With minimal suppression and its extremely strong androgenicity, this will enhance sperm production as androgens are necessary to spermatogenesis stimulation. This not only enhances the amount of sperm produced but greatly and equally important enhances the quality of the sperm. Before we go any further understand Proviron does have the ability to suppress gonadotropins, but there’s a line that has to be crossed for notable suppression to interfere with sperm production. This will make sense once we dive into the side effects section.
Effects of Proviron:
During a bulking phase Proviron is not going to be a foundational steroid, and for most men it will not have a place in an off-season cycle. There are exceptions and we’ll go over those here. Adding in Proviron could possibly help the individual breakthrough a sticking point during his cycle. At some point and time in all cycles the progress begins to wane, and in some cases come to a complete halt. By the way Proviron enhances the total free state of the other steroids being used in a stack, it could possibly help the individual breakthrough this sticking point. During the off-season, this is where most will use the largest amount of testosterone. Many will use large amounts during cutting cycles too, especially competitive bodybuilders but lower testosterone plans are more common during the cutting phase. However, there are those for numerous reasons who choose to run off-season cycles with limited testosterone doses. In such plans, including Proviron could give them a slight needed androgen boost. While it may not always be necessary it could prove to be beneficial.
Without question the best time to use Proviron will be during the cutting phase. This steroid has the ability to provide a bit of a hardening effect similar to Masteron, but more importantly the hardening effects of other steroids will be enhanced. Then we consider its strong binding to the androgen receptor, which will in fact enable the individual to burn body fat at a far more efficient rate. From here we must consider the anti-estrogen effect of Proviron. This will ensure the individual is less prone to water retention and as discussed, depending on the total cycle, it could negate the need for a traditional anti-estrogen. Then we’re once again left with the enhancement of circulating free testosterone. This can be a tremendous benefit when testosterone levels are often much lower during this phase of anabolic steroid use. In fact, with a low dosed testosterone cycle that includes other anabolic steroids, we can confidently say the total results will be greater for the individual who includes Proviron compared to the one who does not. In the end, the primary base benefit is the increased androgenicity of other steroids being used in order to promote a much harder and far more defined physique. It should be noted while Proviron can most certainly provide these traits they will not be noticeable unless you are lean.
Proviron Dosages and cycles:
Standard Proviron doses to treat androgen or male fertility will normally fall in the 50-75mg per day range. Normally the total dosing is split into 2-3 25mg doses per day. In androgen deficiency plans, the total dosing almost always starts at 75mg per day and slowly reduces to 25-50mg per day depending on patient need.
In a performance capacity, Proviron doses normally range from 50-150mg per day. Most men, however, will find 100mg per day to be the minimum beneficial dose with both 100mg and 150mg being highly effective. Total use will normally last between 8-12 weeks. However, in an effort to breakthrough a sticking point in a cycle, say towards the end of a cycle a 6 week course of Proviron may do the trick.
When you’re planning your Proviron use, you will find it stacks well with all anabolic steroids. During the cutting phase it will be most beneficial in conjunction with steroids like Anavar, Masteron and Winstrol as well as Primobolan. It will greatly promote the androgenicity of these steroids in order to provide and promote the hard look desired. In a bulking phase, while it will stack well with all anabolic steroids it’s hard to say if you’ll need it or not. Some will simply keep it on hand and include it when it proves to be possibly necessarily beneficial.
Proviron is not what we can call an extremely powerful anabolic steroid and we cannot really put it in a similar class that we would many other steroids. However, this is still a very beneficial anabolic steroid. It’s simply not beneficial in the traditional way in which we often view anabolic steroids. This is hard for many to accept, as message boards, while there are good ones many have brainwashed others into an improper view of anabolic steroids. In some ways, these individuals are just as guilty as the anti-steroid crowd when it comes to misinformation. Luckily for you, that should no longer be a problem when it comes to Proviron.
If used for the right purposes and with an understanding of the hormone, Proviron could potentially transform many of your cycles. Will this be the end all be all that sees a radical transformation acquired? Probably not, but it will provide benefits that others steroids cannot and simply round out your cycle in a way that will be hard to beat.
Studies have shown proviron is effective for depression, anxiety and to boost lack of sex drive. Hence, it would make sense that those with bipolar, unipolar, and dysthymia would benefit from this hormone. It’s generally prescribed by doctors to men with low libido. In addition, it’s a precursor to full TRT (testosterone replacement therapy).
Proviron was popularized years ago as an anti-estrogen because it is has a high affinity to bind to the aromatase enzyme, so anabolic steroid (AS) users could use it to serve as their AI (aromatase inhibitor) replacement. Bodybuilders were using it during post cycle therapy (PCT); unfortunately, studies have shown proviron does suppress LH (luteinizing hormone) – in some cases. As a result, high proviron dosage can prevent the pituitary gland from recovering after a steroid cycle. Some users insist proviron does not suppress the HPTA when used in PCT or during a bridge; however, this is up for debate. As a side note, some studies support long term use of proviron at high dosages without serious suppression. The science supports proviron use for PCT but not in every case.
Now that we have aromasin, arimidex, and letrozole, proviron has become obsolete when it comes to anti-estrogen usage. We know that the true aromatase inhibitors (AI) are safe to use during post cycle therapy, and will not suppress your HPTA. Though, proviron shouldn’t either.
In this respect, it doesn’t mean proviron does not have its uses on cycle when using an aromatizing compound such as dianabol, testosterone, nandrolones, or equipoise. In fact, a user can expect to have a harder look, more vascularity, and less puffiness when stacking proviron with a wet compound.
Another benefit of proviron is that it binds very well to SHBG (sex hormone binding globulin), which is the hormone responsible for reducing free testosterone circulating in the body. This is probably the reason why some use proviron during PCT.
Those that compete will appreciate proviron’s hardening properties. Since proviron is 5-alpha reduced and not capable of forming estrogen, it will help give a drier look.
Stacking vs. Not:
Since it has no anabolic properties, proviron is worthless when used alone by a bodybuilder. However, when stacked, it can turn a wet compound into a perfect balance of size and hardness for your muscles. My favorite oral stack is dianabol and proviron at 25mgs each per day. I did not get the normal bloated and puffy muscle look from dbol alone as the proviron helped balance it out. Since proviron is a non c17 alpha-alkylated compound, it is safe to stack with an oral.
Proviron can be stacked with any anabolic steroid safely. In fact, it’s been called oral masteron by many, and rightfully so.
Sample Proviron Cycle:
Week Dianabol Proviron Cardarine (GW) N2Guard
1 40mgs/ED 50mgs/ED 20mgs/ED 5caps/ED
2 40mgs/ED 50mgs/ED 20mgs/ED 5caps/ED
3 40mgs/ED 50mgs/ED 20mgs/ED 5caps/ED
4 40mgs/ED 50mgs/ED 20mgs/ED 5caps/ED
5 40mgs/ED 50mgs/ED 20mgs/ED 5caps/ED
6 40mgs/ED 50mgs/ED 20mgs/ED 5caps/ED
7 40mgs/ED 50mgs/ED 20mgs/ED 5caps/ED
8 40mgs/ED 50mgs/ED 20mgs/ED 5caps/ED
Dosages and Half Life:
The half life of proviron is around 12 hours. A good recommended dosage is 25-75mg per day; though, I have personally never exceeded 50mg a day in a stack. The detection time is 5-6 weeks. so those that are tested often would be wise to avoid this compound. Females are not advised to take proviron because of its DHT properties. Side effects for females can be very nasty and unpredictable.